Supplement Facts Serving Size: 1 Tablet Serving per box: 30 Tablet Amt. Per Serving Pycnogenol Pine Bark Extract 50mg (Pinus pinaster) (bark) 60% Oligomeric Proanthocyanidins 30mg Clinically Proven ORAL TREATMENT Dose: 2 capsules daily for atleast 3 months Abridged Prescribing Information: Composition: Pycnogenol capsule: Each capsule contains Proanthocyanidins 50 mg,(Pinus pinaster) (bark) 60% Oligomeric Proanthocyanidins 30mg, Indications Skin disorders & melasma, Diabetes allergy, asthma, hypertension associated with complications endometriosis, dysmenorrhea, retinopathy and osteoarthritis. Dosage and Administration 1-2 Tablet daily for at least 3 months or advised by the physician. Side effects: Tablet.Pycnol Plus generally well tolerated, it should be taken with meals to avoid gastric upset, diarrhea and constipation Rare adverse effects such as headache and dizziness may occur. Contraindications: None known. Pregnancy and Lactation. As a general precaution, pregnant women should not take within the first 3 months of pregnancy. Drug Interactions: None known. Packs: Pycnol Plus Tablet: Each box Contains 30 Tablet in blister pack Manufactured by Herbal Division, Agnus Pharmacutycals (India) Reference: Camila A. S. Pinto, Manuela F. Z. Delfes, Larissa M. dos Reis, Luiz E. Garbers, Paola C. V da R. Passos, Deborah S. de Torre, The use of pycnogenol in the treatment of melasma. Surg Cosmet Dermatol 2015:7 (3):218-22